Skin Firming Treatment with Biomimetic Peptides.
Simildiet Xtra Skin Firming mesotherapy can be used with a dermapen, dermaroller or with microneedling therapy.
Skin Firming treatment with this product acts stimulating cell proliferation and the MECs synthesis. Favours fibres regeneration (collagen and elastin) hyaluronic, proteoglycans, restoring aging and flaccid skin and skin with lack of elasticity and firmness, bring back smoothness.
This product can be used on the face or body.
The topical application of Xtra Skin Firming fights the effects of skin aging, significantly increasing the genetic.
OBJECTIVE
To determine the effects of the Xtra Skin Firming product on collagen 1 and Elastin gene expression, after topical application on medaka (Oryzias latipes)
eleutheroembryos.
COMPOSITION
• 12 Vitamins • 24 Aminoacids
• 4 Coenzymes • 4 Minerals
• 4 Nucleic acids • 2 Antioxidants
• Sodium hyaluronate 1.5% • DMAE
• Hydrosoluble collagen • Methylsilanol mannuronate
• 5 Biomimetic peptides
PRODUCTS TESTED
Bionos Biotech (entity depending and supported by the Polytechnic University of Valencia) received the product to be analysed on 03/31/2017 at room temperature and it was labelled as indicated: P.0630: XTRA Skin Firming
The component was stored at 4°C in Bionos Biotech, to avoid alteration of the product.
METODOLOGY
XTRA Skin Firming was applied topically on the medaka eleutheroembryos during 5 minutes. After 2 hours (response time), mRNA was purified and quantified and it was used to synthesize complementary DNA (cDNA). This cDNA from treated and untreated embryos (control) was used to determine the relative gene expression of Col 1 and Eln through real-time quantitative PCR.
CONCLUSIONS
The results show that the topical application of Xtra Skin Firming fights
the effects of skin aging, significantly increasing the genetic
expression of Col 1 gene.